We are aware that basic knowledge about the process of aging is essential to develop novel anti-aging therapies. Understanding why we age will help us to slow down or reverse aging. For these reasons, one of our major goals is to communicate our discoveries as publications in high-quality scientific journals.
"In vivo amelioration of age-associated hallmarks by partial reprogramming"
Ocampo, A. et al. Cell (2016)
“Metabolic rescue in pluripotent cells from patients with mtDNA disease”
Ma, H. et al. Nature (2015)
"A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging"
Zhang, W. et al. Science Magazine (2015)
“Selective elimination of mitochondrial mutations in the germline by genome editing”
Reddy, P., Ocampo, A. et al. Cell (2015)
"Cellular reprogramming and the rise of rejuvenation biotech"
Magalhães, JP., et al. Trends in Biotechnology (2022)
"High concordance between hippocampal transcriptome of the mouse intra‐amygdala kainic acid model and human temporal lobe epilepsy"
Parras, A. et al., Epilepsia (2020)
"Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy"
Parras, A. et al. Brain (2020)
“NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded / oligomerized proteins”
Ocampo, A. et al. Hum. Mol. Genet (2013)
"Mitochondrial respiratory thresholds regulate Yeast chronological life span and its extension by caloric restriction"
Ocampo, A. et al. Cell Metabolism (2012)
“Quick and reliable assessment of chronological life span in yeast cell populations by flow cytometry”
Ocampo, A. et al. Mech Ageing Dev (2011)
“Developing yeast models of human neurodegenerative disorders”
Ocampo, A. et al. Methods Mol Biol (2011)
“Suppression of polyglutamine-induced cytotoxicity in Saccharomyces cerevisiae by enhancement of mitochondrial biogenesis"
Ocampo, A. et al. FASEB J (2009)
“From the bakery to brain business: developing inducible models of human neurodegenerative disorders”
Ocampo, A. et al. Biotechniques (2008)