Scientific publications
We are aware that basic knowledge about the process of aging is essential to develop novel anti-aging therapies. Understanding why we age will help us to slow down or reverse aging. For these reasons, one of our major goals is to communicate our discoveries as publications in high-quality scientific journals.
Highlighted Publications
"DNA repair-deficient premature aging models display accelerated epigenetic age"
Perez K., et al. Aging Cell (2023)
"In vivo reprogramming leads to premature death linked to hepatic and intestinal failure"
Parras A., et al. Nature Aging (2023)
"In vivo amelioration of age-associated hallmarks by partial reprogramming"
Ocampo A., et al. Cell (2016)
“Selective elimination of mitochondrial mutations in the germline by genome editing”
Reddy P., Ocampo A., et al. Cell (2015)
Additional Publications
"Association between prescription drugs and all-cause mortality risk in the UK population"
Morin J., et al. medRxiv (2024)
"Comparative analysis of mouse strains for in vivo reprogramming"
Picó S., et al. bioRxiv (2024)
"Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging"
Paine P.T., et al. Frontiers in Aging (2024)
"Partial cellular reprogramming: A deep dive into an emerging rejuvenation technology"
Paine P.T., et al. Aging Cell (2023)
"Vitamin B12 emerges as key player during cellular reprogramming"
Vilchez-Acosta A., et al. Nat Metab. (2023)
"ATAC-clock: An aging clock based on chromatin accessibility"
Morandini F., et al. Geroscience (2023)
"Chemical reprogramming ameliorates cellular hallmarks of aging and extends lifespan"
Schoenfeldt L., et al. bioRxiv (2022)
"Cellular reprogramming and the rise of rejuvenation biotech"
Magalhães JP., et al. Trends in Biotechnology (2022)
“Anti-aging strategies based on cellular reprogramming”
Ocampo A., et al. Trends Mol Med (2016)
“Holding your breath for longevity”
Ocampo A., et al. Science (2015)
“NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded / oligomerized proteins”
Ocampo A., et al. Hum. Mol. Genet (2013)
"Mitochondrial respiratory thresholds regulate Yeast chronological life span and its extension by caloric restriction"
Ocampo A., et al. Cell Metabolism (2012)
“Quick and reliable assessment of chronological life span in yeast cell populations by flow cytometry”
Ocampo A., et al. Mech Ageing Dev (2011)
“Developing yeast models of human neurodegenerative disorders”
Ocampo A., et al. Methods Mol Biol (2011)
“Suppression of polyglutamine-induced cytotoxicity in Saccharomyces cerevisiae by enhancement of mitochondrial biogenesis"
Ocampo A., et al. FASEB J (2009)
“From the bakery to brain business: developing inducible models of human neurodegenerative disorders”
Ocampo A., et al. Biotechniques (2008)
Click in this link for a full list of publications of Prof. Alejandro Ocampo.